Article
Investigation of elements sufficient to imprint the mouse Air promoter.
Molecular and cellular biology - 1 Aug 2001
Sleutels F, Barlow D P
Abstract excerpt
Imprinted maternal-allele-specific expression of the mouse insulin-like growth-factor type 2 receptor (Igf2r) gene depends on a 3.7-kb element named region 2, located in the second intron of the gene. Region 2 carries a maternal-allele-specific methylation imprint and contains an imprinted CpG island promoter (Air) that expresses a noncoding antisense RNA from the paternal inherited allele only. Here, we use...
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