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Article

Genomic imprinting of the IGF2R/AIR locus is conserved between bovines and mice.

Theriogenology - 1 Mar 2022

Liu Xiaoqian, Huo Haonan, Jin Lanjie, Dong Yanqiu, Li Dongjie, Zhang Cui, Li Shijie

Abstract excerpt

Genomic imprinting is an epigenetic phenomenon that leads to genes monoallelically expressed in a parent-of-origin-specific manner and plays an important role in the embryonic development and postnatal growth of mammals. Imprinted genes usually occur in clusters in a chromosomal region and are regulated by a cis-acting imprinting control region that involves differential DNA methylation modification. Igf2r,...

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PMID: 34971973
DOI: 10.1016/j.theriogenology.2021.12.013

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