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Article

Human CD8+ CTL recognition and in vitro lysis of herpes simplex virus-infected cells by a non-MHC restricted mechanism.

Scandinavian journal of immunology - 1 Jan 2002

Garland R J, El-Shanti N, West S E, Hancock J P, Goulden N J, Steward C G, Rowbottom A W

Abstract excerpt

Cytotoxic T lymphocytes (CTL) are important for the recognition and lysis of virally infected cells, but their effectiveness can be limited by viral immune evasion mechanisms. We investigated the immunophenotype and function of human CD8+ T cells raised in response to herpes simplex virus (HSV). The expanded population contained cells of an activated and mature phenotype, as determined by the expressions of CD25,...

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Source

Identifiers

PMID: 11841693
DOI: 10.1046/j.1365-3083.2002.01021.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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