Infection and inhibition of human cytotoxic T lymphocytes by herpes simplex virus.

doi:10.1128/JVI.68.6.4072-4074.1994

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Article

Infection and inhibition of human cytotoxic T lymphocytes by herpes simplex virus.

Journal of virology - 1 Jun 1994

Posavad C M, Newton J J, Rosenthal K L

Abstract excerpt

The effect of herpes simplex virus type 1 (HSV-1) infection on human cytotoxic T-lymphocyte (CTL) lytic function was assessed. All HSV-infected CTL populations tested were significantly inhibited in lysing target cells. The inhibition of CTL lytic function by infection with HSV-1 was independent...

Topics

Cytotoxicity, Immunologic
Herpes Simplex
Herpesvirus 1, Human
Humans
Immediate-Early Proteins
In Vitro Techniques
Isoantigens
Lymphocyte Culture Test, Mixed
Mutation
T-Lymphocytes, Cytotoxic
Tumor Cells, Cultured

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