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Article

Infection and inhibition of human cytotoxic T lymphocytes by herpes simplex virus.

Journal of virology - 1 Jun 1994

Posavad C M, Newton J J, Rosenthal K L

Abstract excerpt

The effect of herpes simplex virus type 1 (HSV-1) infection on human cytotoxic T-lymphocyte (CTL) lytic function was assessed. All HSV-infected CTL populations tested were significantly inhibited in lysing target cells. The inhibition of CTL lytic function by infection with HSV-1 was independent of T-cell receptor-mediated antigen recognition and did not involve virus-induced shutoff of host protein synthesis,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8189546
DOI: 10.1128/JVI.68.6.4072-4074.1994
PMCID: PMC236920

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Source receipt: pubmed, retrieved 7 Sept 2026.

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