Article
Testing for genetic linkage in families by a variance-components approach in the presence of genomic imprinting.
American journal of human genetics - 1 Mar 2002
Shete Sanjay, Amos Christopher I
Abstract excerpt
Some genes that affect development and behavior in mammals are known to be imprinted; and > or = 1% of all mammalian genes are imprinted. Hence, incorporating an imprinting parameter into linkage analysis may increase the power to detect linkage for these traits. Here we propose theoretical justifications for a recently developed model for testing of linkage, in the presence of genetic imprinting, between a...
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