Article
A statistical framework for genome-wide scanning and testing of imprinted quantitative trait loci.
Journal of theoretical biology - 7 Jan 2007
Cui Yuehua
Abstract excerpt
Non-equivalent expression of alleles at a locus results in genomic imprinting. In this article, a statistical framework for genome-wide scanning and testing of imprinted quantitative trait loci (iQTL) underlying complex traits is developed based on experimental crosses of inbred line species in backcross populations. The joint likelihood function is composed of four component likelihood functions with each of...
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