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Article

Leptin concentrations in GH deficiency: the effect of GH insensitivity.

The Journal of clinical endocrinology and metabolism - 1 Feb 2002

Marzullo Paolo, Buckway Caroline, Pratt Katherine L, Colao Annamaria, Guevara-Aguirre Jaime, Rosenfeld Ron G

Abstract excerpt

Disorders of GH secretion are known to impair the physiological lipostat and to affect the secretion of leptin, a sensitive marker of regional fat accumulation and total body composition. In both children and adults with GH deficiency (GHD), leptin levels are increased proportionately with enhanced adiposity. In GHI, mutations of the GH receptor gene result in a phenotype similar to GHD, with increased adiposity...

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Source

Identifiers

PMID: 11836282
DOI: 10.1210/jcem.87.2.8229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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