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Article

The inhibition of growth hormone secretion presented in obesity is not mediated by the high leptin levels: a study in human leptin deficiency patients.

The Journal of clinical endocrinology and metabolism - 1 Jan 2003

Ozata Metin, Dieguez Carlos, Casanueva Felipe F

Abstract excerpt

GH secretion is regulated by hypothalamic and peripheral hormones under a very complex interplay. Superimposed on this regulation, signals of a metabolic nature connect GH secretion with the metabolic and energetic homeostasis of a given individual. GH secretion is enhanced in malnutrition and is severely impeded in obesity, but no information is available to explain why GH secretion is severely impeded or...

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Source

Identifiers

PMID: 12519870
DOI: 10.1210/jc.2002-020122

Genes

GHRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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