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Article

Impact of the growth hormone receptor exon 3 deletion gene polymorphism on glucose metabolism, lipids, and insulin-like growth factor-I levels during puberty.

The Journal of clinical endocrinology and metabolism - 1 Aug 2009

Sørensen Kaspar, Aksglaede Lise, Munch-Andersen Thor, Aachmann-Andersen Niels Jacob, Leffers Henrik, Helge Jørn Wulff, Hilsted Linda, Juul Anders

Abstract excerpt

CONTEXT: The GH/IGF-I axis has major impact on insulin sensitivity and insulin secretion. Recently a polymorphism in the GH receptor gene (GHR), a genomic deletion of exon 3 (GHRd3), has been linked to increased responsiveness to GH. OBJECTIVE: The objective of the present study was to evaluate the impact of the GHRd3 gene polymorphism on insulin sensitivity, insulin secretion, lipids, and IGF-I levels in healthy...

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Source

Identifiers

PMID: 19417039
DOI: 10.1210/jc.2009-0313

Genes

GHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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