Article
Partial growth hormone deficiency in adults; should we be looking for it?
Clinical endocrinology - 1 Oct 2010
Shalet Stephen M
Abstract excerpt
Quantitatively, GH secretion exists as a continuum in states ranging from good health through to hypopituitarism. Currently, GH replacement is considered only for adults designated as being severely GH deficient (GHD). In clinical practice the gold standard, on which the biochemical diagnosis of severe GHD is based, centres on the presence of two or more additional anterior pituitary hormone deficits. Cohorts of...
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