Serum leptin in obese patients with Laron syndrome before and during IGF-I treatment.

doi:10.1515/JPEM.1998.11.5.653

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Article

Serum leptin in obese patients with Laron syndrome before and during IGF-I treatment.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2000

Laron Z, Silbergeld A, Lilos P, Blum F W

Abstract excerpt

Fifteen patients with primary GH resistance (Laron syndrome, LS) were studied before and during 6 months of daily replacement treatment with IGF-I. The main findings were that patients with LS and normal or high serum GH binding protein (GHBP) were less obese than those with a negative GHBP, and...

Topics

Adult
Body Composition
Carrier Proteins
Child
Child, Preschool
Drug Resistance
Female
Human Growth Hormone
Humans
Infant
Insulin
Insulin-Like Growth Factor I
Leptin
Male
Mutation
Obesity
Proteins
Receptors, Leptin

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