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Article

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance.

American journal of human genetics - 1 Mar 2002

Di Paola Rosa, Frittitta Lucia, Miscio Giuseppe, Bozzali Maura, Baratta Roberto, Centra Marta, Spampinato Daniela, Santagati Maria Grazia, Ercolino Tonino, Cisternino Carmela, Soccio Teresa, Mastroianno Sandra, Tassi Vittorio, Almgren Peter, Pizzuti Antonio, Vigneri Riccardo, Trischitta Vincenzo

Abstract excerpt

Protein tyrosine phosphatase 1B (PTP1B) inhibits insulin signaling and, when overexpressed, plays a role in insulin resistance (Ahmad et al. 1997). We identified, in the 3' untranslated region of the PTP1B gene, a 1484insG variation that, in two different populations, is associated with several f...

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Identifiers

PMID: 11833006
DOI: 10.1086/339270
PMCID: PMC384960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11833006-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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