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Article

Structural diversity of heparan sulfate binding domains in chemokines.

Proceedings of the National Academy of Sciences of the United States of America - 5 Feb 2002

Lortat-Jacob Hugues, Grosdidier Aurélien, Imberty Anne

Abstract excerpt

Heparan sulfate (HS) molecules are ubiquitous in animal tissues where they function as ligands that are dramatically involved in the regulation of the proteins they bind. Of these, chemokines are a family of small proteins with many biological functions. Their well-conserved monomeric structure can associate in various oligomeric forms especially in the presence of HS. Application of protein surface analysis and...

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Identifiers

PMID: 11830659
DOI: 10.1073/pnas.032497699
PMCID: PMC122172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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