Article
Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation.
Development (Cambridge, England) - 1 Feb 2002
Fu Hui, Qi Yingchuan, Tan Min, Cai Jun, Takebayashi Hirohide, Nakafuku Masato, Richardson William, Qiu Mengsheng
Abstract excerpt
In this study, we have investigated the relationship of Olig2+ and Nkx2.2+ oligodendrocyte progenitors (OLPs) by comparing the expression of Olig2 and Nkx2.2 in embryonic chicken and mouse spinal cords before and during the stages of oligodendrogenesis. At the stages of neurogenesis, Olig2 and Nkx2.2 are expressed in adjacent non-overlapping domains of ventral neuroepithelium. During oligodendrogenesis stages,...
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