Article
NG2-positive cells generate A2B5-positive oligodendrocyte precursor cells.
Glia - 1 Aug 2007
Baracskay Karen L, Kidd Grahame J, Miller Robert H, Trapp Bruce D
Abstract excerpt
Cellular specification of the oligodendrocyte lineage occurs through a series of stages identified by expression of distinct biochemical characteristics. The best characterized oligodendrocyte progenitor cell (OPC) in vitro is the bipotential O2-A progenitor, identified by labeling with monoclonal antibody A2B5, which proliferates predominantly in response to platelet derived growth factor (PDGF). The cellular...
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