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Article

Modulation of dendritic cell phenotype and function in an in vitro model of the intestinal epithelium.

European journal of immunology - 1 Apr 2006

Butler Matt, Ng Chi-Yan, van Heel David A, Lombardi Giovanna, Lechler Robert, Playford Raymond J, Ghosh Subrata

Abstract excerpt

A network of dendritic cells (DC) can be detected in close proximity to the epithelial cells overlying Peyer's patches in the gut. Intestinal DC show distinct phenotypes as compared to DC from the systemic lymph nodes (relatively low MHC and costimulatory molecules and high IL-10 and TGFbeta) and may play a role in maintaining tolerance to enteric antigens. We show that a similar phenotype is induced in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16544275
DOI: 10.1002/eji.200535497

Genes

TLR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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