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Article

Lack of association between juvenile idiopathic arthritis and fas gene polymorphism.

The Journal of rheumatology - 1 Jan 2002

Donn Rachelle, Zeggini Eleftheria, Shelley Emma, Ollier William, Thomson Wendy

Abstract excerpt

OBJECTIVE: Juvenile idiopathic arthritis (JIA) is a complex genetic disease of autoimmune etiology. Fas is a molecule with a pivotal role in apoptosis and hence in immune regulation. Elevated transcriptional levels of Fas in the synovial fluid of patients with JIA suggest that it might be implicated in disease etiopathogenesis. We investigated whether a polymorphism in the Fas promoter region (-670) confers...

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PMID: 11824955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lack of association between juvenile idiopathic arthritis and fas gene polymorphism.PMID 11824955Read ↗

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