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Article

Tumour necrosis factor receptor II polymorphism and juvenile idiopathic arthritis.

Rheumatology (Oxford, England) - 1 Apr 2002

Zeggini E, Thomson W, Alansari A, Ollier W, Donn R

Abstract excerpt

OBJECTIVES: Juvenile idiopathic arthritis (JIA) is a complex polygenic disorder. The encouraging outcome of anti-tumour necrosis factor (TNF) treatment, as well as serological studies, has implicated TNF and its receptors (TNFRI and TNFRII, or TNFRSF1B) in the pathogenesis of JIA. The purpose of this study was to investigate the exon 6 TNFRII single nucleotide polymorphism (SNP) in a well-defined UK cohort of JIA...

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Share to Antigens, CD
Share to Arthritis, Juvenile

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Tumor Necrosis Factor

Share to Receptors, Tumor Necrosis Factor, Type II

Source

Identifiers

PMID: 11961180
DOI: 10.1093/rheumatology/41.4.462

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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