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Article

A Fas promoter polymorphism at position -670 in the enhancer region does not confer susceptibility to Felty's and large granular lymphocyte syndromes.

Rheumatology (Oxford, England) - 1 Sept 1999

Coakley G, Manolios N, Loughran T P, Panayi G S, Lanchbury J S

Abstract excerpt

OBJECTIVE: We examined whether there are associations between a polymorphism in the Fas promoter, recently found to be associated with rheumatoid arthritis (RA), and Felty's syndrome or large granular lymphocyte (LGL) leukaemia. METHODS: Thirty-five patients with Felty's were studied, along with 18 patients with LGL syndrome and arthritis, 17 patients with LGL syndrome but no arthritis, and 128 controls. The...

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Share to Aged, 80 and over
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

Share to fas Receptor

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Share to Leukemia, Lymphoid

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 10515651
DOI: 10.1093/rheumatology/38.9.883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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