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Article

Folic acid prevents exencephaly in Cited2 deficient mice.

Human molecular genetics - 1 Feb 2002

Barbera Juan Pedro Martinez, Rodriguez Tristan A, Greene Nicholas D E, Weninger Wolfgang J, Simeone Antonio, Copp Andrew J, Beddington Rosa S P, Dunwoodie Sally

Abstract excerpt

Cited2 (also Mrg1/p35srj) is a member of a new conserved gene family that is expressed during mouse development and in adult tissues. In order to investigate the function of Cited2 during mouse embryogenesis, we introduced a null mutation into the Cited2 locus. Cited2(-/-) mutants died at late gestation and exhibited heart defects and exencephaly, arising from defective closure of the midbrain (MB) and hindbrain....

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Source

Identifiers

PMID: 11823447
DOI: 10.1093/hmg/11.3.283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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