Article
The role of murMN operon in penicillin resistance and antibiotic tolerance of Streptococcus pneumoniae.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2001
Filipe S R, Severina E, Tomasz A
Abstract excerpt
The recently identified murMN operon is essential for the production of branched-structured muropeptides in the cell wall and also for the expression of the resistant phenotype in penicillin-resistant strains of Streptococcus pneumoniae. The purpose of studies described in this communication was to understand better the role of murMN in penicillin resistance. Deletion of murM in the penicillin-resistant strain...
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