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Article

Role of murE in the Expression of beta-lactam antibiotic resistance in Staphylococcus aureus.

Journal of bacteriology - 1 Mar 2004

Gardete S, Ludovice A M, Sobral R G, Filipe S R, de Lencastre H, Tomasz A

Abstract excerpt

It was shown earlier that Tn551 inserted into the C-terminal region of murE of parental methicillin-resistant Staphylococcus aureus strain COL causes a drastic reduction in methicillin resistance, accompanied by accumulation of UDP-MurNAc dipeptide in the cell wall precursor pool and incorporation of these abnormal muropeptides into the peptidoglycan of the mutant. Methicillin resistance was recovered in a...

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Identifiers

PMID: 14996801
DOI: 10.1128/JB.186.6.1705-1713.2004
PMCID: PMC355982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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