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Article

Interaction of the molecular chaperone Hsp70 with human NAD(P)H:quinone oxidoreductase 1.

The Journal of biological chemistry - 19 Apr 2002

Anwar Adil, Siegel David, Kepa Jadwiga K, Ross David

Abstract excerpt

NAD(P)H:quinone oxidoreductase 1 (EC; DT-Diaphorase, NQO1) is predominantly a cytosolic flavoenzyme that catalyzes a two-electron reduction. Using human tumor cell lines devoid of NQO1 enzymatic activity, we have previously identified a single nucleotide polymorphism (NQO1*2 allele) in the human NQO1 gene. This mutation has been characterized as a genetic polymorphism (NQO1*2), which leads to greatly diminished...

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Source

Identifiers

PMID: 11821413
DOI: 10.1074/jbc.M111576200

Genes

NQO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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