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Article

Cooperative action of Hsp70, Hsp90, and DnaJ proteins in protein renaturation.

Biochemistry - 26 Nov 1996

Schumacher R J, Hansen W J, Freeman B C, Alnemri E, Litwack G, Toft D O

Abstract excerpt

The proteins required for the repair of damaged proteins in the eukaryotic cytoplasm remain largely uncharacterized. The renaturation of thermally denatured firefly luciferase readily occurs in rabbit reticulocyte lysate by an ATP-dependent process. Earlier studies had shown that this chaperoning activity could be reconstituted, in part, using purified preparations of hsp70 and hsp90. We have extended the...

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PMID: 8942653
DOI: 10.1021/bi961825h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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