Influence of angiotensin-I-converting-enzyme insertion/deletion gene polymorphism on perioperative hemodynamics after coronary bypass graft surgery.

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Article

Influence of angiotensin-I-converting-enzyme insertion/deletion gene polymorphism on perioperative hemodynamics after coronary bypass graft surgery.

The Journal of cardiovascular surgery - 1 Apr 2008

Popov A F, Hinz J, Liakopoulos O J, Schmitto J D, Seipelt R, Quintel M, Schoendube F A

Abstract excerpt

AIM: The angiotensin I-converting enzyme insertion/ deletion polymorphism (ACE-I/D), including three genotypes (II, ID, DD), with a known impact on midterm mortality and morbidity in patients after coronary artery bypass graft surgery (CABG), was studied. Since this polymorphism has been linked with increased vascular response to phenylephrine during cardiopulmonary bypass (CPB), we investigated its possible...

Topics

Aged
Blood Pressure
Cardiopulmonary Bypass
Central Venous Pressure
Coronary Artery Bypass
Female
Genotype
Hemodynamics
Humans
INDEL Mutation
Male
Peptidyl-Dipeptidase A
Polymorphism, Genetic
Vascular Resistance

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Open in PubMed

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PMID: 18431347

Genes

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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