Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Clostridium ramosum IgA Proteinase Represents a Novel Type of Metalloendopeptidase

1 Apr 2002

Abstract excerpt

Clostridium ramosum is part of the normal flora in the human intestine. Some strains produce an IgA proteinase that specifically cleaves human IgA1 and the IgA2m(1) allotype. This prolylendopeptidase was purified from a broth culture supernatant, and N-terminal sequences of the native protein and tryptic fragments thereof were determined. A fragment of the iga gene encoding the IgA proteinase was isolated using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical and Structural Characterization
Share to Clostridium difficile and Clostridium perfringens research
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11815614
DOI: 10.1074/jbc.m110883200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Clostridium ramosum IgA Proteinase Represents a Novel Type of MetalloendopeptidasePMID 11815614Read ↗

Occurrence and Evolution of the Paralogous Zinc Metalloproteases IgA1 Protease, ZmpB, ZmpC, and ZmpD in Streptococcus pneumoniae and Related Commensal SpeciesSemantic proximity Read ↗

Group A streptococcal SpeB modifies IgA through targeting regions other than the hingeSemantic proximity Read ↗

IgA Function in Relation to the Intestinal MicrobiotaSemantic proximity Read ↗

Neisseria meningitidis IgA1-specific serine protease exhibits novel cleavage activity against IgG3Semantic proximity Read ↗

Comparative analysis of immunoglobulin A1 protease activity among bacteria representing different genera, species, and strainsSemantic proximity Read ↗

The Influences of Hinge Length and Composition on the Susceptibility of Human IgA to Cleavage by Diverse Bacterial IgA1 ProteasesSemantic proximity Read ↗

A comparative genetic study of serologically distinct Haemophilus influenzae type 1 immunoglobulin A1 proteases.Semantic proximity Read ↗

Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase (Lys-gingipain) in Porphyromonas gingivalis: structural relationship with the arginine-specific cysteine proteinase (Arg-gingipain).Semantic proximity Read ↗

Molecular polymorphism and epidemiology of Neisseria meningitidis immunoglobulin A1 proteases.Semantic proximity Read ↗

Effect of mutations in the human immunoglobulin A1 (IgA1) hinge on its susceptibility to cleavage by diverse bacterial IgA1 proteases.Semantic proximity Read ↗

The Neisseria type 2 IgA1 protease cleaves LAMP1 and promotes survival of bacteria within epithelial cells.Semantic proximity Read ↗

Adaptive evolution of the IgA hinge region in primates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.