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Article

Molecular polymorphism and epidemiology of Neisseria meningitidis immunoglobulin A1 proteases.

Proceedings of the National Academy of Sciences of the United States of America - 15 Mar 1992

Lomholt H, Poulsen K, Caugant D A, Kilian M

Abstract excerpt

Neisseria meningitidis is one of several important bacterial pathogens that secrete a specific protease capable of cleaving human immunoglobulin A1 (IgA1) in the hinge region. To obtain further information on this putative virulence factor, we examined the IgA1 protease and iga gene region of 133...

Topics

Carrier State
Chromosomes, Bacterial
DNA, Bacterial
Genes, Bacterial
Genotype
Humans
Immunoglobulin A
Meningitis, Meningococcal
Neisseria meningitidis
Peptide Hydrolases
Polymorphism, Genetic
Serine Endopeptidases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serotyping

Source

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Identifiers

PMID: 1549571
DOI: 10.1073/pnas.89.6.2120
PMCID: PMC48608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1549571-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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