IgA Function in Relation to the Intestinal Microbiota

Abstract excerpt

IgA is the dominant immunoglobulin isotype produced in mammals, largely secreted across the intestinal mucosal surface. Although induction of IgA has been a hallmark feature of microbiota colonization following colonization in germ-free animals, until recently appreciation of the function of IgA in host-microbial mutualism has depended mainly on indirect evidence of alterations in microbiota composition or...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Clostridium difficile and Clostridium perfringens research
• Share to Gut microbiota and health
• Share to T-cell and B-cell Immunology