Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic identification of two distinct DNA polymerases, DnaE and PolC, that are essential for chromosomal DNA replication in Staphylococcus aureus.

Molecular genetics and genomics : MGG - 1 Dec 2001

Inoue R, Kaito C, Tanabe M, Kamura K, Akimitsu N, Sekimizu K

Abstract excerpt

We isolated and characterized temperature-sensitive mutants for two genes, dnaE and polC, that are essential for DNA replication in Staphylococcus aureus. DNA replication in these mutants had a slow-stop phenotype when the temperature was shifted to a non-permissive level. The dnaE gene encodes a homolog of the alpha-subunit of the DNA polymerase III holoenzyme, the replicase essential for chromosomal DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Bacterial
Share to DNA-Directed DNA Polymerase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Polymerase III

Share to DNA Replication

Share to Exodeoxyribonuclease V

Share to Exodeoxyribonucleases

Share to Genetic Complementation Test

Share to Staphylococcus aureus

Source

Identifiers

PMID: 11810227
DOI: 10.1007/s004380100564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic identification of two distinct DNA polymerases, DnaE and PolC, that are essential for chromosomal DNA replication in Staphylococcus aureus.PMID 11810227Read ↗

Isolation and characterization of temperature-sensitive mutants of the Staphylococcus aureus dnaC gene.Semantic proximity Read ↗

Isolation of a temperature-sensitive dnaA mutant of Staphylococcus aureus.Semantic proximity Read ↗

A temperature-sensitive mutation in the dnaE gene of Caulobacter crescentus that prevents initiation of DNA replication but not ongoing elongation of DNA.Semantic proximity Read ↗

Identification of temperature-sensitive dnaD mutants of Staphylococcus aureus that are defective in chromosomal DNA replication.Semantic proximity Read ↗

Overproduction of DnaE protein (alpha subunit of DNA polymerase III) restores viability in a conditionally inviable Escherichia coli strain deficient in DNA polymerase I.Semantic proximity Read ↗

An rpsL-based allelic exchange vector for Staphylococcus aureus.Semantic proximity Read ↗

Novel alleles of the Escherichia coli dnaA gene.Semantic proximity Read ↗

Novel Escherichia coli active site dnaE alleles with altered base and sugar selectivity.Semantic proximity Read ↗

Two essential DNA polymerases at the bacterial replication fork.Semantic proximity Read ↗

Sequence analysis and phenotypes of five temperature sensitive mutator alleles of dnaE, encoding modified alpha-catalytic subunits of Escherichia coli DNA polymerase III holoenzyme.Semantic proximity Read ↗

Characterization of dnaC2 and dnaC28 mutants by flow cytometry.Semantic proximity Read ↗

Isolation and characterization of herpes simplex virus mutants containing engineered mutations at the DNA polymerase locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.