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Article

Two essential DNA polymerases at the bacterial replication fork.

Science (New York, N.Y.) - 23 Nov 2001

Dervyn E, Suski C, Daniel R, Bruand C, Chapuis J, Errington J, Jannière L, Ehrlich S D

Abstract excerpt

DNA replication in bacteria is carried out by a multiprotein complex, which is thought to contain only one essential DNA polymerase, specified by the dnaE gene in Escherichia coli and the polC gene in Bacillus subtilis. Bacillus subtilis genome analysis has revealed another DNA polymerase gene, dnaE(BS), which is homologous to dnaE. We show that, in B. subtilis, dnaE(BS) is essential for cell viability and for...

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Source

Identifiers

PMID: 11721055
DOI: 10.1126/science.1066351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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