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Article

Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line.

Nucleic acids research - 1 Feb 2002

Yáñez Rafael J, Porter Andrew C G

Abstract excerpt

Overexpression of the RAD52 epistasis group of gene products is a convenient way to investigate their in vivo roles in homologous recombination (HR) and DNA repair. Overexpression has the further attraction that any associated stimulation of HR may facilitate gene-targeting applications. Rad51p or Rad52p overexpression in mammalian cells have previously been shown to enhance some forms of HR and resistance to...

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Topics

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Share to Cell Cycle
Share to Chromosomes, Human
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

Share to Gene Targeting

Share to Hypoxanthine Phosphoribosyltransferase

Share to Rad51 Recombinase

Share to Rad52 DNA Repair and Recombination Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 11809887
DOI: 10.1093/nar/30.3.740
PMCID: PMC100286

Genes

RAD51
RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line.PMID 11809887Read ↗

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