Article
POB3 is required for both transcription and replication in the yeast Saccharomyces cerevisiae.
Genetics - 1 Aug 2000
Schlesinger M B, Formosa T
Abstract excerpt
Spt16 and Pob3 form stable heterodimers in Saccharomyces cerevisiae, and homologous proteins have also been purified as complexes from diverse eukaryotes. This conserved factor has been implicated in both transcription and replication and may affect both by altering the characteristics of chromatin. Here we describe the isolation and properties of a set of pob3 mutants and confirm that they have defects in both...
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