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Article

Immune diversity and genomic stability: opposite goals but similar paths.

Journal of photochemistry and photobiology. B, Biology - 31 Dec 2001

Jeggo P A, Concannon P

Abstract excerpt

DNA damage response mechanisms serve to protect cells from exogenous and endogenous DNA damaging agents with the aim of maintaining genomic stability. In contrast, the generation of an efficient immune response requires the creation of a repertoire of distinct immunoglobulin and T cell receptor genes able to recognise the huge array of antigens that may be encountered in a lifetime. Surprisingly, cells have...

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Identifiers

PMID: 11809363
DOI: 10.1016/s1011-1344(01)00243-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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