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Article

Primary immunodeficiency syndromes.

Advances in experimental medicine and biology - 1 Jan 2010

Slatter Mary A, Gennery Andrew R

Abstract excerpt

Several DNA repair pathways have evolved to recognise and repair DNA damaged by exogenous and endogenous agents, in order to maintain genomic integrity. Defects in these pathways can lead to replication errors, loss or rearrangement ofgenomic material, mutation or cancer and eventual death. The creation of many diverse lymphocyte receptors to identify potential pathogens has evolved by breaking and randomly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Rearrangement, T-Lymphocyte

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Share to Somatic Hypermutation, Immunoglobulin

Source

Identifiers

PMID: 20687503
DOI: 10.1007/978-1-4419-6448-9_14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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