Article
Differential activity of a variant form of the human Id-1 protein generated by alternative splicing.
FEBS letters - 2 Oct 1998
Tamura Y, Sugimoto M, Ohnishi K, Sakai T, Hara E
Abstract excerpt
Members of the Id family of helix-loop-helix proteins are ubiquitously expressed and dimerize with members of the class A and class B basic helix-loop-helix proteins. Due to the absence of a basic region, Id proteins act as dominant-negative antagonists of basic helix-loop-helix transcription fac...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Cloning, Molecular
- Fibroblasts
- Genetic Variation
- Helix-Loop-Helix Motifs
- Humans
- Inhibitor of Differentiation Protein 1
- Mice
- Molecular Sequence Data
- Recombinant Proteins
- Repressor Proteins
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Alignment
- Sequence Homology, Amino Acid