Article
Differential activity of a variant form of the human Id-1 protein generated by alternative splicing.
FEBS letters - 2 Oct 1998
Tamura Y, Sugimoto M, Ohnishi K, Sakai T, Hara E
Abstract excerpt
Members of the Id family of helix-loop-helix proteins are ubiquitously expressed and dimerize with members of the class A and class B basic helix-loop-helix proteins. Due to the absence of a basic region, Id proteins act as dominant-negative antagonists of basic helix-loop-helix transcription factors, which regulate cell growth and differentiation in diverse cell types. Recent findings suggest that the functions...
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