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Inhibitor of DNA binding in heart development and cardiovascular diseases

24 May 2019

Abstract excerpt

Id proteins, inhibitors of DNA binding, are transcription regulators containing a highly conserved helix-loop-helix domain. During multiple stages of normal cardiogenesis, Id proteins play major roles in early development and participate in the differentiation and proliferation of cardiac progenitor cells and mature cardiomyocytes. The fact that a depletion of Ids can cause a variety of defects in cardiac...

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PMID: 31126344
DOI: 10.1186/s12964-019-0365-z

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