Article
Regulation of mammary epithelial cell phenotypes by the helix-loop-helix protein, Id-1.
Endocrine-related cancer - 1 Mar 1999
Lin C Q, Parrinello S, Campisi J, Desprez P Y
Abstract excerpt
Mammary epithelial cells undergo cycles of proliferation, invasion, differentiation and apoptotic cell-death throughout adult life. The molecular mechanisms that regulate these complex and co-ordinated developmental programs are poorly understood. We have identified Id-1 protein, a negative regulator of basic helix-loop-helix transcription factors, as a critical regulator of these normal mammary epithelial cell...
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