Article
Carboxyl tail prevents yeast K(+) channel closure: proposal of an integrated model of TOK1 gating.
Biophysical journal - 1 Feb 2002
Loukin Stephen H, Saimi Yoshiro
Abstract excerpt
TOK1 encodes the channel responsible for the prominent outward K(+) current of the yeast plasma membrane. It can dwell in several impermeable states, including a rapidly transiting, K(+)-electromotive-force-dependent "R" (rectifying) state, a voltage-independent "IB" (interburst) state, and a set of [K(+)](ext) and voltage-dependent "C" (closed) states. Whereas evidence suggests that the C states result from the...
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