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Article

Mutations in the yeast two pore K+ channel YKC1 identify functional differences between the pore domains.

FEBS letters - 24 Sept 1999

Vergani P, Blatt M R

Abstract excerpt

The K+ channel of Saccharomyces cerevisiae encoded by the YKC1 gene includes two pore-loop sequences that are thought to form the hydrophilic lining of the pore. Gating of the channel is promoted by membrane depolarisation and is regulated by the extracellular K+ concentration ([K+]o) both in the yeast and when expressed in Xenopus oocytes. Our previous work showed that substitutions of equivalent residues L293...

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Identifiers

PMID: 10570925
DOI: 10.1016/s0014-5793(99)01167-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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