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Article

Novel Real-Time Quantitative PCR Test for Trisomy 21

1 Feb 2002

Abstract excerpt

The detection of gross chromosomal abnormalities is a major focus of invasive prenatal diagnosis testing, of which the most common cytogenetic anomaly in live births is trisomy 21 (Down syndrome). Classically these examinations are lengthy procedures relying on karyotypic analysis of cultured amniocytes or chorionic mesenchyme. More rapid alternatives, such as fluorescence in situ hybridization and quantitative...

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Share to Genomic variations and chromosomal abnormalities
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Identifiers

PMID: 11805021
DOI: 10.1093/clinchem/48.2.362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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