Article
Recombination-based screening for genes on chromosome 21.
American journal of medical genetics. Supplement - 1 Jan 1990
Stewart G D, Kurnit D M
Abstract excerpt
In previous work, a reasonably large number of genes was found to be on chromosome 21. This frequency demands the creation of new techniques to investigate the transcription of this small human autosome, and to relate these findings to the phenotype of Down syndrome. Here we describe the elaborat...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 21
- Cloning, Molecular
- Cosmids
- Down Syndrome
- Flow Cytometry
- Humans
- Phenotype
- Recombination, Genetic
- Transcription, Genetic