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Article

Molecular diagnosis of Down syndrome using quantitative APEX-2 microarrays.

Prenatal diagnosis - 1 Dec 2010

Oitmaa Eneli, Peters Maire, Vaidla Kadri, Andreson Reidar, Mägi Reedik, Slavin Georgi, Velthut Agne, Tõnisson Neeme, Reimand Tiia, Remm Maido, Schneider Marion, Ounap Katrin, Salumets Andres, Metspalu Andres

Abstract excerpt

OBJECTIVE: To develop a new rapid and high-throughput microarray-based prenatal diagnostic test for the detection of trisomy 21 (T21). METHODS: The T21 arrayed primer extension-2 (APEX-2) assay discriminates between trisomy and euploid DNA samples by comparing the signal intensities of allelic fr...

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PMID: 20949644
DOI: 10.1002/pd.2639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20949644-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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