Article
Altered mammary epithelial development, pattern formation and involution in transgenic mice expressing the EphB4 receptor tyrosine kinase.
Journal of cell science - 1 Jan 2002
Munarini Nadia, Jäger Richard, Abderhalden Susanne, Zuercher Gisela, Rohrbach Valeria, Loercher Saemi, Pfanner-Meyer Brigitte, Andres Anne-Catherine, Ziemiecki Andrew
Abstract excerpt
We have previously documented the cell-type-specific and hormone-dependent expression of the EphB4 receptor in the mouse mammary gland. To investigate its role in the biology of the mammary gland, we have established transgenic mice bearing the EphB4 receptor under the control of the MMTV-LTR promoter, which represents the first transgenic mouse model to investigate the effect(s) of unscheduled expression of...
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