Article
A novel doxycycline‐inducible system for the transgenic analysis of mammary gland biology
1 Mar 2002
Abstract excerpt
Normal developmental events such as puberty, pregnancy, and parity influence the susceptibility of the mammary gland to tumorigenesis in both humans and rodent model systems. Unfortunately, constitutive transgenic mouse models that rely on mammary-specific promoters to control transgene expression have limited utility for studying the effect of developmental events on breast cancer risk since the hormonal signals...
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