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Article

Testing for genetic association in the presence of linkage and gene-covariate interactions.

Biometrical journal. Biometrische Zeitschrift - 1 Feb 2010

Callegaro Andrea, Lebrec Jeremie J P, Houwing-Duistermaat Jeanine J

Abstract excerpt

In order to study family-based association in the presence of linkage, we extend a generalized linear mixed model proposed for genetic linkage analysis (Lebrec and van Houwelingen (2007), Human Heredity 64, 5-15) by adding a genotypic effect to the mean. The corresponding score test is a weighted family-based association tests statistic, where the weight depends on the linkage effect and on other genetic and...

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Identifiers

PMID: 20166130
DOI: 10.1002/bimj.200900057
PMCID: PMC3410551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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