Article
Practical application of residuals from survival models in quantitative trait linkage analysis.
Genetic epidemiology - 1 Jan 2001
Yoo B, Pankratz V S, de Andrade M
Abstract excerpt
A number of familial diseases have an age-of-onset component, which can be considered as a censored quantitative trait. However, few software resources are available for the use of time-to-event endpoints in linkage analysis. The purpose of this analysis was to examine the use of martingale residuals from Cox survival models as quantitative traits for familial diseases with variable age at onset. We used these...
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