Article
Interval mapping methods for detecting QTL affecting survival and time-to-event phenotypes.
Genetical research - 1 Apr 2005
Moreno C R, Elsen J M, Le Roy P, Ducrocq V
Abstract excerpt
Quantitative trait loci (QTL) are usually searched for using classical interval mapping methods which assume that the trait of interest follows a normal distribution. However, these methods cannot take into account features of most survival data such as a non-normal distribution and the presence of censored data. We propose two new QTL detection approaches which allow the consideration of censored data. One...
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