Article
PGMRA: a web server for (phenotype x genotype) many-to-many relation analysis in GWAS.
Nucleic acids research - 1 Jul 2013
Arnedo Javier, del Val Coral, de Erausquin Gabriel Alejandro, Romero-Zaliz Rocío, Svrakic Dragan, Cloninger Claude Robert, Zwir Igor
Abstract excerpt
It has been proposed that single nucleotide polymorphisms (SNPs) discovered by genome-wide association studies (GWAS) account for only a small fraction of the genetic variation of complex traits in human population. The remaining unexplained variance or missing heritability is thought to be due to marginal effects of many loci with small effects and has eluded attempts to identify its sources. Combination of...
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