Article
Analysis of single nucleotide polymorphisms in candidate genes using the pedigree disequilibrium test.
Genetic epidemiology - 1 Jan 2001
Hardy S W, Weir B S, Kaplan N L, Martin E R
Abstract excerpt
The pedigree disequilibrium test (PDT) has been proposed recently as a test for association in general pedigrees [Martin et al., Am J Hum Genet 67:146-54, 2000]. The Genetic Analysis Workshop (GAW) 12 simulated data, with many extended pedigrees, is an example the type of data to which the PDT is ideally suited. In replicate 42 from the general population the PDT correctly identifies candidate genes 1, 2, and 6...
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