Article
Multilocus linkage analysis of the German asthma data.
Genetic epidemiology - 1 Jan 2001
Zandi P P, Klein A P, Addington A M, Hetmanski J B, Roberts L, Peila R, Shrestha S, Shaw C K, Kiat H C, Langefeld C D, Beaty T H
Abstract excerpt
We analyzed data from the German Asthma Genetics Group with three methods that utilize pedigree-specific nonparametric linkage scores to facilitate the search for multiple independent and interacting susceptibility loci. The three methods included a conditional analysis, logistic regression, and neural networks. Although there were differences, the three methods identified many of the same susceptibility loci....
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